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Antibody Product Overview
| ELK.No | ES17765 |
| Product name | CCDC6 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8030 |
| Human Swiss-Prot | Q16204 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CCDC6 |
| Fields | >>Pathways in cancer;>>Thyroid cancer |
| Gene name | CCDC6 D10S170 TST1 |
| Protein name | CCDC6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 76551 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | D3YZP9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human CCDC6 AA range: 104-154 |
| Specificity | This antibody detects endogenous levels of CCDC6 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 52kD |
| Observed band (KD) | |
| Background | This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.[provided by RefSeq, Sep 2010], |
| Function | disease:A chromosomal aberration involving CCDC6 is a cause of thyroid papillary carcinoma (PACT) [MIM:188550]. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.,domain:The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.,subcellular location:May be a cytoskeletal protein.,tissue specificity:Ubiquitously expressed., |
| Subcellular location | Cytoplasm. Cytoplasm, cytoskeleton . May be a cytoskeletal protein. |
| Expression | Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17765-50
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