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Antibody Product Overview
| ELK.No | ES17946 |
| Product name | BTBD1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 53339 |
| Human Swiss-Prot | Q9H0C5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BTBD1 |
| Fields | |
| Gene name | BTBD1 C15orf1 NS5ATP8 |
| Protein name | BTBD1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 83962 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P58544 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human BTBD1 AA range: 115-165 |
| Specificity | This antibody detects endogenous levels of BTBD1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 53kD |
| Observed band (KD) | |
| Background | The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BTB (POZ) domain.,subcellular location:Cytoplasmic bodies.,subunit:Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Interacts with CUL3.,tissue specificity:Ubiquitous; higher levels in heart and skeletal muscle., |
| Subcellular location | Cytoplasm . Localizes to punctate or elongated cytoplasmic bodies. . |
| Expression | Ubiquitous; highest levels in testes, heart and skeletal muscle. |
Additional Images
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Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17946-50
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