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Antibody Product Overview
| ELK.No | ES17956 |
| Product name | BRD1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 23774 |
| Human Swiss-Prot | O95696 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BRD1 |
| Fields | |
| Gene name | BRD1 BRL BRPF2 |
| Protein name | BRD1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human BRD1 AA range: 399-449 |
| Specificity | This antibody detects endogenous levels of BRD1 at Human |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 116kD |
| Observed band (KD) | |
| Background | This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schozophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015], |
| Function | function:Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.,similarity:Contains 1 bromo domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain.,subunit:Component of the MOZ/MORF composed at least of ING5, MYST3/MOZ, MYST4/MORF and one of BRPF1, BRD1/BRPF2 and BRPF3.,tissue specificity:Highly expressed in testis., |
| Subcellular location | Nucleus . Chromosome . Localizes to transcription start sites. . |
| Expression | Highly expressed in testis. |
Additional Images
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Western blot analysis of lysates from CACO2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES17956-100
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