| ELK.No | ES1797 |
| Product name | BTF rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9774 |
| Human Swiss-Prot | Q9NYF8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | BCLAF1 |
| Fields | |
| Gene name | BCLAF1 |
| Protein name | Bcl-2-associated transcription factor 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72567 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K019 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330 |
| Specificity | BTF Polyclonal Antibody detects endogenous levels of BTF protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 106kD |
| Background | This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Function | function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous., |
| Subcellular location | Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm . |
| Expression | Ubiquitous. |



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