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Antibody Product Overview
| ELK.No | ES18063 |
| Product name | Beta-defensin 4A Rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | IHC; ELISA |
| Other name | Beta-defensin 4A (Beta-defensin 2;BD-2;hBD-2;Defensin, beta 2;Skin-antimicrobial peptide 1;SAP1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 100289462 |
| Human Swiss-Prot | O15263 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Beta-defensin 4A |
| Fields | >>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>Staphylococcus aureus infection |
| Gene name | DEFB4A DEFB102 DEFB2 DEFB4; DEFB4B |
| Protein name | Beta-defensin 4A |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human Beta-defensin 4A AA range: 1-50 |
| Specificity | This antibody detects endogenous levels of human Beta-defensin 4A |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | IHC-p 1:50-200, ELISA(peptide)1:5000-20000 |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | |
| Background | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008], |
| Function | function:Has antibacterial activity .,induction:By inflammation.,similarity:Belongs to the beta-defensin family. LAP/TAP subfamily.,tissue specificity:Expressed in the skin and respiratory tract., |
| Subcellular location | Secreted. |
| Expression | Expressed in the skin and respiratory tract. |
Additional Images
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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: AO-06-ES18063-100
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