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Antibody Product Overview
| ELK.No | ES18185 |
| Product name | ATX3L rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB |
| Other name | Putative ataxin-3-like protein (EC 3.4.19.12) (Machado-Joseph disease protein 1-like) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 92552 |
| Human Swiss-Prot | Q9H3M9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ATX3L |
| Fields | >>Protein processing in endoplasmic reticulum;>>Spinocerebellar ataxia;>>Pathways of neurodegeneration - multiple diseases |
| Gene name | ATXN3L ATX3L MJDL |
| Protein name | ATX3L |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ATX3L AA range: 99-149 |
| Specificity | This antibody detects endogenous levels of ATX3L at Human |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.64% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This intronless gene may be a pseudogene (PMID:11450850). This gene is similar to the multi-exon gene which encodes ataxin 3 and contains a coding region which could encode a protein similar to ataxin 3. Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease. [provided by RefSeq, Sep 2011], |
| Function | caution:Could be the product of a pseudogene. Suggested by the absence of intron.,function:May bind to histones and regulate transcription. May act as a deubiquitinating enzyme.,similarity:Contains 1 Josephin domain.,similarity:Contains 2 UIM (ubiquitin-interacting motif) repeats., |
| Subcellular location | Nucleus . |
| Expression | Testis, |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18185-50
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