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Antibody Product Overview
| ELK.No | ES18209 |
| Product name | ATG12 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9140 |
| Human Swiss-Prot | O94817 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ATG12 |
| Fields | >>FoxO signaling pathway;>>Autophagy - other;>>Autophagy - animal;>>NOD-like receptor signaling pathway;>>RIG-I-like receptor signaling pathway;>>Shigellosis |
| Gene name | ATG12 APG12 APG12L |
| Protein name | ATG12 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67526 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CQY1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 361321 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q2TBJ5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ATG12 AA range: 80-130 |
| Specificity | This antibody detects endogenous levels of ATG12 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 15kD |
| Observed band (KD) | |
| Background | Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008], |
| Function | function:Required for autophagy.,similarity:Belongs to the ATG12 family.,subunit:Conjugated to ATG5.,tissue specificity:Ubiquitous., |
| Subcellular location | Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane. |
| Expression | Ubiquitous. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18209-50
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