ASTL rabbit pAb

ASTL rabbit pAb

AO-06-ES18225-100

ASTL rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES18225
Product nameASTL rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other name
Size100μL
Unit price ($)248
Human gene ID431705
Human Swiss-ProtQ6HA08
SourceRabbit
IsotypeIgG
TargetASTL
Fields
Gene nameASTL
Protein nameASTL
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID215095
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ6HA09
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human ASTL AA range: 115-165
SpecificityThis antibody detects endogenous levels of ASTL at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)47kD
Observed band (KD)
Background
Functionenzyme regulation:Inhibited by wide spectrum metalloproteinase inhibitor batimastat (BB-94). Also inhibited by EDTA.,similarity:Belongs to the peptidase M12A family.,tissue specificity:Expressed in promyelocytic leukemia HL-60 cells, Burkitt's lymphoma Raji cells, and also in some ovarian carcinomas. Not detected in normal tissues.,
Subcellular locationCytoplasm . Cell membrane . Cytoplasmic vesicle, secretory vesicle, Cortical granule . Probably exocytosed from cortical granules during post-fertilization. Detected throughout the ooplasm of germinal vesicle stage oocytes in early bilaminar secondary follicles at postnatal (PN) day 3. Detected in the microvillar domain of the oolemma in arrested ovulated secondary oocytes and in the first polar body prior to fertilization. Upon fertilization, detected in the perivitelline space (PVS) and occasionally on the oolemma in 2-cell through morulae stages. Colocalizes with SPACA3 at the microvillar domain of the oolemma and in the perivitelline space (PVS). .
ExpressionExpressed in promyelocytic leukemia HL-60 cells, Burkitt's lymphoma Raji cells, and also in some ovarian carcinomas. Not detected in normal tissues.

Additional Images

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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18225-100
: 10 Produits
Hurry! only 10 items left in stock.

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