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Antibody Product Overview
| ELK.No | ES18258 |
| Product name | ARID2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 196528 |
| Human Swiss-Prot | Q68CP9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ARID2 |
| Fields | >>Hepatocellular carcinoma |
| Gene name | ARID2 KIAA1557 |
| Protein name | ARID2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ARID2 AA range: 309-359 |
| Specificity | This antibody detects endogenous levels of ARID2 at Human |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 202kD |
| Observed band (KD) | |
| Background | ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008], |
| Function | developmental stage:Up-regulated in adult heart (at protein level).,function:Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.,sequence caution:Differs from position 1094 onward for unknown reason.,similarity:Contains 1 ARID domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF2 |
| Subcellular location | Nucleus. |
| Expression | Highly expressed in heart. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18258-50
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