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Antibody Product Overview
| ELK.No | ES18259 |
| Product name | ARI3B rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | AT-rich interactive domain-containing protein 3B (ARID domain-containing protein 3B) (Bright and dead ringer protein) (Bright-like protein) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10620 |
| Human Swiss-Prot | Q8IVW6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ARI3B |
| Fields | |
| Gene name | ARID3B BDP DRIL2 |
| Protein name | ARI3B |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56380 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z1N7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ARI3B AA range: 459-509 |
| Specificity | This antibody detects endogenous levels of ARI3B at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.83% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright and Drosophila dead ringer proteins. A pseudogene on chromosome 1p31 exists for this gene. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008], |
| Function | function:Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.,similarity:Contains 1 ARID domain.,subunit:Heterodimer with ARID3A. Interacts with unphosphorylated RB1.,tissue specificity:Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level)., |
| Subcellular location | Nucleus . |
| Expression | Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K-562 erythrocytic leukemia cell line (at protein level). |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18259-100
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