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Antibody Product Overview
| ELK.No | ES18304 |
| Product name | AP4B1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10717 |
| Human Swiss-Prot | Q9Y6B7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AP4B1 |
| Fields | >>Lysosome |
| Gene name | AP4B1 |
| Protein name | AP4B1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67489 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9WV76 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human AP4B1 AA range: 595-645 |
| Specificity | This antibody detects endogenous levels of AP4B1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 81kD |
| Observed band (KD) | |
| Background | This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011], |
| Function | function:Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.,similarity:Belongs to the adaptor complexes large subunit family.,subcellular location:Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.,subunit:Adapter-like complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1 and beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1).,tissue specificity:Widely expressed., |
| Subcellular location | Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . |
| Expression | Widely expressed. |
Additional Images
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Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18304-100
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