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Antibody Product Overview
| ELK.No | ES18445 |
| Product name | AF1L1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Actin filament-associated protein 1-like 1 (AFAP1-like protein 1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 134265 |
| Human Swiss-Prot | Q8TED9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | AF1L1 |
| Fields | |
| Gene name | AFAP1L1 |
| Protein name | AF1L1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 106877 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BZI0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 291565 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | D4AB98 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human AF1L1 AA range: 180-230 |
| Specificity | This antibody detects endogenous levels of AF1L1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.325% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | |
| Function | PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PH domains., |
| Subcellular location | Cytoplasm . Cell projection, podosome . Cell projection, invadopodium . Cytoplasm, cytoskeleton, stress fiber . |
| Expression | Expressed in breast, colon and brain. In all 3 tissues, expressed in the microvasculature (at protein level). In addition, in the breast, found in the contractile myoepithelial cell layer which surrounds the breast ducts (at protein level). In the colon, expressed in the mucous membrane and colonic crypts and in the smooth muscle cell layer which provide movement of the colon (at protein level). In the cerebellum, localized around the Purkinje neurons and the granule cells of the granular layer, but not inside cell bodies (at protein level). Outside of the cerebellar cortex, expressed in glial cells (at protein level). Highly expressed away from the cell bodies within the dentate nucleus (at protein level). |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18445-50
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