AEBP2 rabbit pAb

AEBP2 rabbit pAb

AO-06-ES18446-50

AEBP2 rabbit pAb 50μL

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299,00 €
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Antibody Product Overview

ELK.NoES18446
Product nameAEBP2 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB
Other name
Size50μL
Unit price ($)148
Human gene ID121536
Human Swiss-ProtQ6ZN18
SourceRabbit
IsotypeIgG
TargetAEBP2
Fields
Gene nameAEBP2
Protein nameAEBP2
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID11569
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9Z248
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human AEBP2 AA range: 155-205
SpecificityThis antibody detects endogenous levels of AEBP2 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)57kD
Observed band (KD)
Background
Functionfunction:DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.,sequence caution:Translated as Gln.,similarity:Belongs to the AEBP2/jing C2H2-type zinc-finger family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Self-associates. Interacts with EED, EZH2, RBBP4 and SUZ12. Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2 (By similarity). May also interact with RBBP7.,
Subcellular locationNucleus . Localizes to chromatin as part of the PRC2 complex. .
Expression

Additional Images

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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18446-50
: 10 Produits
Hurry! only 10 items left in stock.

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