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Antibody Product Overview
| ELK.No | ES18504 |
| Product name | ACADL rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 33 |
| Human Swiss-Prot | P28330 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ACADL |
| Fields | >>Fatty acid degradation;>>Metabolic pathways;>>Fatty acid metabolism;>>PPAR signaling pathway |
| Gene name | ACADL |
| Protein name | ACADL |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 11363 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P51174 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25287 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P15650 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ACADL AA range: 258-308 |
| Specificity | This antibody detects endogenous levels of ACADL at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 47kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.,cofactor:FAD.,disease:Impaired ACADL activity results in non-ketotic hypoglycemia, hypotonia, muscle weakness and episodes of cardiorespiratory arrest associated with fasting [MIM:201460].,miscellaneous:A number of straight-chain acyl-CoA dehydrogenases of different substrate specificities are present in mammalian tissues.,pathway:Lipid metabolism; mitochondrial fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA dehydrogenase family.,subunit:Homotetramer., |
| Subcellular location | Mitochondrion matrix . |
| Expression |
Additional Images
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Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18504-100
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