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Antibody Product Overview
| ELK.No | ES18508 |
| Product name | ABR rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 29 |
| Human Swiss-Prot | Q12979 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ABR |
| Fields | |
| Gene name | ABR |
| Protein name | ABR |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 109934 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q5SSL4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ABR AA range: 393-443 |
| Specificity | This antibody detects endogenous levels of ABR at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 94kD |
| Observed band (KD) | |
| Background | This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis. Alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Feb 2012], |
| Function | function:GTPase-activating protein for RAC and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them.,similarity:Contains 1 C2 domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Highly enriched in the brain. Much weaker expression in heart, lung and muscle., |
| Subcellular location | Cell projection, dendritic spine . Cell projection, axon . Cell junction, synapse . |
| Expression | Highly enriched in the brain. Much weaker expression in heart, lung and muscle. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18508-100
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