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Antibody Product Overview
| ELK.No | ES18513 |
| Product name | ABCB9 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 23457 |
| Human Swiss-Prot | Q9NP78 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ABCB9 |
| Fields | >>ABC transporters;>>Lysosome |
| Gene name | ABCB9 KIAA1520 |
| Protein name | ABCB9 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56325 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JJ59 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 63886 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9QYJ4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ABCB9 AA range: 224-274 |
| Specificity | This antibody detects endogenous levels of ABCB9 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.312% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities. [provided by RefSeq, Jul 2011], |
| Function | function:May function as a peptide transporter.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. MHC peptide exporter (TC 3.A.1.209) subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid., |
| Subcellular location | Lysosome membrane ; Multi-pass membrane protein . May be located in membrane rafts. Takes an intracellular route from the endoplasmic reticulum (ER), via Golgi and early endosomes to late endosomal and lysosomal compartments (PubMed:30877195). . |
| Expression | Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES18513-50
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