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Antibody Product Overview
| ELK.No | ES1904 |
| Product name | CD2BP2 rabbit pAb |
| Reactivity | Human;Monkey |
| Applications | WB;IHC;IF;ELISA |
| Other name | CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10421 |
| Human Swiss-Prot | O95400 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD2BP2 |
| Fields | |
| Gene name | CD2BP2 |
| Protein name | CD2 antigen cytoplasmic tail-binding protein 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9CWK3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150 |
| Specificity | CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008], |
| Function | similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain., |
| Subcellular location | Cytoplasm. Nucleus. Predominantly nuclear. |
| Expression | Aorta,Brain,Epithelium,Liver,Lung, |
Additional Images
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Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1:1000
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Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Western blot analysis of lysates from COS7 cells, using CD2 Tail-binding Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using CD2 Tail-binding antibody.
: AO-06-ES1904-100
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