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Antibody Product Overview
| ELK.No | ES1915 |
| Product name | CD70 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 970 |
| Human Swiss-Prot | P32970 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD70 |
| Fields | >>Cytokine-cytokine receptor interaction |
| Gene name | CD70 |
| Protein name | CD70 antigen |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O55237 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117 |
| Specificity | CD70 Polyclonal Antibody detects endogenous levels of CD70 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008], |
| Function | function:Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer., |
| Subcellular location | Membrane ; Single-pass type II membrane protein . |
| Expression | B-cell,Kidney, |
Additional Images
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Western Blot analysis of various cells using CD70 Polyclonal Antibody diluted at 1:2000
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Western blot analysis of the lysates from Jurkat cells using CD70 antibody.
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: AO-06-ES1915-100
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