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Antibody Product Overview
| ELK.No | ES2013 |
| Product name | CNG-2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IF;ELISA |
| Other name | CNGA2; CNCA; CNCA1; CNCG2; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; CNG2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1260 |
| Human Swiss-Prot | Q16280 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CNG-2 |
| Fields | >>cAMP signaling pathway;>>Olfactory transduction |
| Gene name | CNGA2 |
| Protein name | Cyclic nucleotide-gated olfactory channel |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 12789 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q62398 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25411 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q00195 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CNGA2. AA range:391-440 |
| Specificity | CNG-2 Polyclonal Antibody detects endogenous levels of CNG-2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 83kD |
| Background | The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010], |
| Function | function:Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.,similarity:Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.,similarity:Contains 1 cyclic nucleotide-binding domain., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Testis, |
Additional Images
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Western Blot analysis of various cells using CNG-2 Polyclonal Antibody
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Western Blot analysis of K562 cells using CNG-2 Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES2013-50
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