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Antibody Product Overview
| ELK.No | ES2027 |
| Product name | Connexin 25 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 375519 |
| Human Swiss-Prot | Q6PEY0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Connexin 25 |
| Fields | |
| Gene name | GJB7 |
| Protein name | Gap junction beta-7 protein |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70 |
| Specificity | Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 24kD |
| Background | Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008], |
| Function | function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . |
| Expression | Weakly expressed in placenta. |
Additional Images
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Western Blot analysis of various cells using Connexin 25 Polyclonal Antibody diluted at 1:500
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Western blot analysis of lysates from HT-29 cells, using GJB7 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HeLa cells using GJB7 antibody.
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: AO-06-ES2027-100
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