Français
English
Antibody Product Overview
| ELK.No | ES2060 |
| Product name | CSP rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | DNAJC5; CSP; DnaJ homolog subfamily C member 5; Cysteine string protein; CSP |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 80331 |
| Human Swiss-Prot | Q9H3Z4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CSP |
| Fields | >>Protein processing in endoplasmic reticulum |
| Gene name | DNAJC5 |
| Protein name | DnaJ homolog subfamily C member 5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 13002 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P60904 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 79130 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P60905 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human DNAJC5. AA range:131-180 |
| Specificity | CSP Polyclonal Antibody detects endogenous levels of CSP protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010], |
| Function | function:May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.,PTM:Fatty acylated. Heavily palmitoylated in the cysteine string motif.,similarity:Contains 1 J domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart., |
| Subcellular location | Cytoplasm, cytosol . Membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane . Melanosome . Cell membrane . The association with membranes is regulated by palmitoylation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). . |
| Expression | Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart. |
Additional Images
No image
Western Blot analysis of various cells using CSP Polyclonal Antibody diluted at 1:2000
No image
Western blot analysis of the lysates from HeLa cells using DNAJC5 antibody.
No image
No image
: AO-06-ES2060-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package