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Antibody Product Overview
| ELK.No | ES20678 |
| Product name | LDHD rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB |
| Other name | Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 197257 |
| Human Swiss-Prot | Q86WU2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LDHD |
| Fields | >>Pyruvate metabolism;>>Metabolic pathways |
| Gene name | LDHD |
| Protein name | Probable D-lactate dehydrogenase, mitochondrial |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 52815 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q7TNG8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein of LDHD |
| Specificity | The antibody detects endogenous LDHD protein. |
| Formulation | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Clonality | Polyclonal |
| Dilution | WB: 1:1000-5000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kD |
| Background | The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.,cofactor:FAD.,similarity:Belongs to the FAD-binding oxidoreductase/transferase type 4 family.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Interacts with CSRP3.,tissue specificity:Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney., |
| Subcellular location | Mitochondrion . |
| Expression | Expressed moderately in heart and liver and at lower levels in skeletal muscle and kidney. |
Additional Images
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Western blot analysis of 1) Hela, 2) Mouse Skeletal Muscle, 3) Mouse Liver, 4) Rat Kidney, diluted at 1:5000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES20678-50
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