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Antibody Product Overview
| ELK.No | ES2158 |
| Product name | DDX54 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | DDX54; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 79039 |
| Human Swiss-Prot | Q8TDD1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DDX54 |
| Fields | |
| Gene name | DDX54 |
| Protein name | ATP-dependent RNA helicase DDX54 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8K4L0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from DDX54 . at AA range: 570-650 |
| Specificity | DDX54 Polyclonal Antibody detects endogenous levels of DDX54 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 99kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Function | caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors.,similarity:Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts in a hormone-dependent manner with nuclear receptors., |
| Subcellular location | Nucleus, nucleolus . |
| Expression | Expressed in the fallopian tube, cervix and uterus. Also expressed in the brain. |
Additional Images
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Western Blot analysis of various cells using DDX54 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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: AO-06-ES2158-100
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