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Antibody Product Overview
| ELK.No | ES2201 |
| Product name | DREG rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;IF;ELISA |
| Other name | GPR126; DREG; VIGR; G-protein coupled receptor 126; Developmentally regulated G-protein-coupled receptor; Vascular inducible G protein-coupled receptor |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 57211 |
| Human Swiss-Prot | Q86SQ4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | DREG |
| Fields | |
| Gene name | GPR126 |
| Protein name | G-protein coupled receptor 126 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 215798 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6F3F9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPR126. AA range:1091-1140 |
| Specificity | DREG Polyclonal Antibody detects endogenous levels of DREG protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 140kD |
| Background | This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009], |
| Function | function:Orphan receptor.,polymorphism:Genetic variations in GPR126 influences stature as a quantitative trait (STQTL) [MIM:606255]. Adult height is an easily observable and highly heritable complex continuous trait. Because of this, it is a model trait for studying genetic influence on quantitative traits.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 1 pentaxin domain., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Detected on the cell surface of activated but not resting umbilical vein. . |
| Expression | Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells. |
Additional Images
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Western Blot analysis of various cells using DREG Polyclonal Antibody
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Immunofluorescence analysis of HUVEC cells, using GPR126 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES2201-50
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