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Antibody Product Overview
| ELK.No | ES2260 |
| Product name | Endo G-L1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | EXOG; ENDOGL1; ENDOGL2; ENGL; Nuclease EXOG; mitochondrial; Endonuclease G-like 1; Endo G-like 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9941 |
| Human Swiss-Prot | Q9Y2C4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Endo G-L1 |
| Fields | |
| Gene name | EXOG |
| Protein name | Nuclease EXOG mitochondrial |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8C163 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ENDOGL1. AA range:171-220 |
| Specificity | Endo G-L1 Polyclonal Antibody detects endogenous levels of Endo G-L1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009], |
| Function | cofactor:Divalent metal cations.,function:Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single stranded DNA and 5'-3' exonuclease activity.,miscellaneous:The active site contains 1 hydrated divalent metal cation that has only 1 direct interaction with the protein; all other interactions are via water molecules.,similarity:Belongs to the DNA/RNA non-specific endonuclease family.,subunit:Homodimer.,tissue specificity:Ubiquitous., |
| Subcellular location | Mitochondrion inner membrane . |
| Expression | Ubiquitous. |
Additional Images
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Western Blot analysis of various cells using Endo G-L1 Polyclonal Antibody
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Western blot analysis of lysates from HUVEC, HT-29, and HepG2 cells, using ENDOGL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2260-100
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