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Antibody Product Overview
| ELK.No | ES2343 |
| Product name | Fibulin-2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | FBLN2; Fibulin-2; FIBL-2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2199 |
| Human Swiss-Prot | P98095 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Fibulin-2 |
| Fields | |
| Gene name | FBLN2 |
| Protein name | Fibulin-2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P37889 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290 |
| Specificity | Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 130kD |
| Background | This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary., |
| Subcellular location | Secreted, extracellular space, extracellular matrix. |
| Expression | Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary. |
Additional Images
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Western Blot analysis of various cells using Fibulin-2 Polyclonal Antibody diluted at 1:500
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Immunofluorescence analysis of A549 cells, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.
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: AO-06-ES2343-100
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