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Antibody Product Overview
| ELK.No | ES2379 |
| Product name | Fucokinase rabbit pAb |
| Reactivity | Human;Mouse;Monkey |
| Applications | WB;IF;ELISA |
| Other name | FUK; L-fucose kinase; Fucokinase |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 197258 |
| Human Swiss-Prot | Q8N0W3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Fucokinase |
| Fields | >>Fructose and mannose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars |
| Gene name | FUK |
| Protein name | L-fucose kinase |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FUK. AA range:11-60 |
| Specificity | Fucokinase Polyclonal Antibody detects endogenous levels of Fucokinase protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 110kD |
| Background | fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family., |
| Subcellular location | cytoplasm,cytosol, |
| Expression | Expressed in fibroblasts. |
Additional Images
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Western Blot analysis of various cells using Fucokinase Polyclonal Antibody
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Immunofluorescence analysis of NIH/3T3 cells, using FUK Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from COS7 cells, treated with insulin 0.01U/ml 45', using FUK Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2379-100
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