Français
English
Antibody Product Overview
| ELK.No | ES2388 |
| Product name | GABAA Rα6 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2559 |
| Human Swiss-Prot | Q16445 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GABAA Rα6 |
| Fields | >>Neuroactive ligand-receptor interaction;>>Retrograde endocannabinoid signaling;>>GABAergic synapse;>>Taste transduction;>>Morphine addiction;>>Nicotine addiction |
| Gene name | GABRA6 |
| Protein name | Gamma-aminobutyric acid receptor subunit alpha-6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14399 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P16305 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29708 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P30191 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110 |
| Specificity | GABAA Rα6 Polyclonal Antibody detects endogenous levels of GABAA Rα6 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 51kD |
| Background | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008], |
| Function | function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho., |
| Subcellular location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Expression | Cerebellum, |
Additional Images
No image
Western Blot analysis of various cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500
No image
Western Blot analysis of MOUSE-BRAIN cells using GABAA Rα6 Polyclonal Antibody diluted at 1:500
No image
Western blot analysis of lysates from HeLa and Jurkat cells, using GABRA6 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
: AO-06-ES2388-100
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package