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Antibody Product Overview
| ELK.No | ES2391 |
| Product name | GADD 45γ rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | GADD45G; CR6; DDIT2; Growth arrest and DNA damage-inducible protein GADD45 gamma; Cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein; DDIT-2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10912 |
| Human Swiss-Prot | O95257 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GADD 45γ |
| Fields | >>MAPK signaling pathway;>>NF-kappa B signaling pathway;>>FoxO signaling pathway;>>Cell cycle;>>p53 signaling pathway;>>Apoptosis;>>Cellular senescence;>>Epstein-Barr virus infection;>>Pathways in cancer;>>Transcriptional misregulation in cancer;>>Colorectal cancer;>>Pancreatic cancer;>>Endometrial cancer;>>Glioma;>>Thyroid cancer;>>Basal cell carcinoma;>>Melanoma;>>Chronic myeloid leukemia;>>Small cell lung cancer;>>Non-small cell lung cancer;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer |
| Gene name | GADD45G |
| Protein name | Growth arrest and DNA damage-inducible protein GADD45 gamma |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9Z111 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 291005 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9WTQ7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GA45G. AA range:101-150 |
| Specificity | GADD 45γ Polyclonal Antibody detects endogenous levels of GADD 45γ protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 19kD |
| Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008], |
| Function | function:Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.,similarity:Belongs to the GADD45 family.,subunit:Interacts with GADD45GIP1., |
| Subcellular location | nucleus,cytoplasm, |
| Expression | Brain,Colon carcinoma,Lung,Placenta, |
Additional Images
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Western Blot analysis of various cells using GADD 45γ Polyclonal Antibody
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Western blot analysis of GA45G Antibody. The lane on the right is blocked with the GA45G peptide.
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Immunofluorescence analysis of A549 cells, using GA45G Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using GA45G Antibody. The picture on the right is blocked with the synthesized peptide.
: AO-06-ES2391-100
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