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Antibody Product Overview
| ELK.No | ES2636 |
| Product name | IP6K2 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | IP6K2; IHPK2; TCCCIA00113; Inositol hexakisphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; PiUS |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 51447 |
| Human Swiss-Prot | Q9UHH9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IP6K2 |
| Fields | >>Phosphatidylinositol signaling system |
| Gene name | IP6K2 |
| Protein name | Inositol hexakisphosphate kinase 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 76500 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80V72 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 59268 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9R0U1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IP6K2. AA range:161-210 |
| Specificity | IP6K2 Polyclonal Antibody detects endogenous levels of IP6K2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 49kD |
| Background | This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family., |
| Subcellular location | Nucleus . |
| Expression | Caudate nucleus,Glial tumor,Leukemia,Lung,Skin,Uterus, |
Additional Images
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Western Blot analysis of various cells using IP6K2 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Immunofluorescence analysis of COS7 cells, using IP6K2 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HUVEC, COLO, and Jurkat cells, using IP6K2 Antibody. The lane on the right is blocked with the synthesized peptide.
: AO-06-ES2636-100
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