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Antibody Product Overview
| ELK.No | ES2677 |
| Product name | KKIALRE rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | CDKL1; Cyclin-dependent kinase-like 1; Protein kinase p42 KKIALRE; Serine/threonine-protein kinase KKIALRE |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8814 |
| Human Swiss-Prot | Q00532 |
| Source | Rabbit |
| Isotype | IgG |
| Target | KKIALRE |
| Fields | |
| Gene name | CDKL1 |
| Protein name | Cyclin-dependent kinase-like 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8CEQ0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 314198 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q66HE7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDKL1. AA range:281-330 |
| Specificity | KKIALRE Polyclonal Antibody detects endogenous levels of KKIALRE protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 42kD |
| Background | This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013], |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary., |
| Subcellular location | Cytoplasm . Nucleus . |
| Expression | Highly expressed in kidney, and to a lower extent in ovary. |
Additional Images
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Western Blot analysis of various cells using KKIALRE Polyclonal Antibody diluted at 1:500
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Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Western blot analysis of lysates from COLO205 cells, using CDKL1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from COLO205 cells using CDKL1 antibody.
: AO-06-ES2677-100
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