Français
English
Antibody Product Overview
| ELK.No | ES2735 |
| Product name | LYPLA1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;IHC;IF;ELISA |
| Other name | LYPLA1; APT1; LPL1; Acyl-protein thioesterase 1; APT-1; hAPT1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10434 |
| Human Swiss-Prot | O75608 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LYPLA1 |
| Fields | >>Glycerophospholipid metabolism;>>Choline metabolism in cancer |
| Gene name | LYPLA1 |
| Protein name | Acyl-protein thioesterase 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18777 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P97823 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25514 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P70470 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LYPLA1. AA range:51-100 |
| Specificity | LYPLA1 Polyclonal Antibody detects endogenous levels of LYPLA1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013], |
| Function | catalytic activity:Palmitoyl-protein + H(2)O = palmitate + protein.,function:Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Also has low lysophospholipase activity.,similarity:Belongs to the AB hydrolase 2 family.,subunit:Homodimer., |
| Subcellular location | Cytoplasm . Cell membrane . Nucleus membrane . Endoplasmic reticulum . Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum. . |
| Expression | Platelets. |
Additional Images
No image
Western Blot analysis of various cells using LYPLA1 Polyclonal Antibody diluted at 1:2000
No image
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
No image
Western blot analysis of lysates from COLO cells, using LYPLA1 Antibody. The lane on the right is blocked with the synthesized peptide.
No image
Western blot analysis of the lysates from HeLa cells using LYPLA1 antibody.
: AO-06-ES2735-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package