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Antibody Product Overview
| ELK.No | ES2813 |
| Product name | Mos rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | MOS; Proto-oncogene serine/threonine-protein kinase mos; Oocyte maturation factor mos; Proto-oncogene c-Mos |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4342 |
| Human Swiss-Prot | P00540 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Mos |
| Fields | >>Oocyte meiosis;>>Regulation of actin cytoskeleton;>>Progesterone-mediated oocyte maturation |
| Gene name | MOS |
| Protein name | Proto-oncogene serine/threonine-protein kinase mos |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P00536 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MOS. AA range:61-110 |
| Specificity | Mos Polyclonal Antibody detects endogenous levels of Mos protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kD |
| Background | MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009], |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed specifically in testis during spermatogenesis., |
| Subcellular location | intracellular, |
| Expression | Expressed specifically in testis during spermatogenesis. |
Additional Images
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Western Blot analysis of various cells using Mos Polyclonal Antibody
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Western blot analysis of lysates from 293 cells, using MOS Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES2813-100
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