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Antibody Product Overview
| ELK.No | ES2868 |
| Product name | Mucin 13 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | MUC13; DRCC1; RECC; Mucin-13; MUC-13; Down-regulated in colon cancer 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 56667 |
| Human Swiss-Prot | Q9H3R2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Mucin 13 |
| Fields | |
| Gene name | MUC13 |
| Protein name | Mucin-13 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P19467 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MUC13. AA range:421-470 |
| Specificity | Mucin 13 Polyclonal Antibody detects endogenous levels of Mucin 13 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 50kD |
| Background | Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008], |
| Function | function:Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.,PTM:Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds.,PTM:Highly N-glycosylated.,similarity:Contains 1 SEA domain.,similarity:Contains 3 EGF-like domains.,subcellular location:Also exists as a soluble form.,subunit:Homodimer of beta subunits.,tissue specificity:Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . Apical cell membrane . Secreted . Also exists as a soluble form. |
| Expression | Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. |
Additional Images
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Western Blot analysis of various cells using Mucin 13 Polyclonal Antibody diluted at 1:1000
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Western Blot analysis of COLO205 cells using Mucin 13 Polyclonal Antibody diluted at 1:1000
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Immunofluorescence analysis of HepG2 cells, using MUC13 Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using MUC13 Antibody. The picture on the right is blocked with the synthesized peptide.
: AO-06-ES2868-100
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