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Antibody Product Overview
| ELK.No | ES2901 |
| Product name | NBPF7 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC |
| Other name | NBPF7; Putative neuroblastoma breakpoint family member 7 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 343505 |
| Human Swiss-Prot | P0C2Y1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NBPF7 |
| Fields | |
| Gene name | NBPF7 |
| Protein name | Putative neuroblastoma breakpoint family member 7 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NBPF7. AA range:361-410 |
| Specificity | NBPF7 Polyclonal Antibody detects endogenous levels of NBPF7 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 48kD |
| Background | neuroblastoma breakpoint family member 7(NBPF7) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene fam |
| Function | miscellaneous:Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.,similarity:Belongs to the NBPF family.,similarity:Contains 2 NBPF domains., |
| Subcellular location | Cytoplasm . |
| Expression |
Additional Images
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Western Blot analysis of various cells using NBPF7 Polyclonal Antibody
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Western blot analysis of lysates from HT-29 and HepG2 cells, using NBPF7 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES2901-50
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