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Antibody Product Overview
| ELK.No | ES2965 |
| Product name | NKp46 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | NCR1; LY94; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD antigen CD335 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9437 |
| Human Swiss-Prot | O76036 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NKp46 |
| Fields | >>Natural killer cell mediated cytotoxicity |
| Gene name | NCR1 |
| Protein name | Natural cytotoxicity triggering receptor 1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8C567 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194 |
| Specificity | NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kD |
| Background | function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells., |
| Function | function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Selectively expressed by both resting and activated NK cells. |
Additional Images
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Western Blot analysis of various cells using NKp46 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Western blot analysis of lysates from 293, HepG2, MCF-7, and A549 cells, using NCR1 Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES2965-100
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