PMEPA1 rabbit pAb

PMEPA1 rabbit pAb

AO-06-ES3238-100

PMEPA1 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES3238
Product namePMEPA1 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;IHC;IF;ELISA
Other namePMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein
Size100μL
Unit price ($)248
Human gene ID56937
Human Swiss-ProtQ969W9
SourceRabbit
IsotypeIgG
TargetPMEPA1
Fields
Gene namePMEPA1
Protein nameTransmembrane prostate androgen-induced protein
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9D7R2
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenThe antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150
SpecificityPMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)37kD
BackgroundThis gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Functiondomain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary.,
Subcellular locationEarly endosome membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
ExpressionHighest expression in prostate. Also expressed in ovary.

Additional Images

Image 1
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Western Blot analysis of various cells using PMEPA1 Polyclonal Antibody diluted at 1:500
Image 2
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Western Blot analysis of HT29 cells using PMEPA1 Polyclonal Antibody diluted at 1:500
Image 3
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Immunofluorescence analysis of HUVEC cells, using TMEPA Antibody. The picture on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded human prostate tissue, using TMEPA Antibody. The picture on the right is blocked with the synthesized peptide.
: AO-06-ES3238-100
: 10 Produits
Hurry! only 10 items left in stock.

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