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Antibody Product Overview
| ELK.No | ES3293 |
| Product name | Rab 7L1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | RAB7L1; Ras-related protein Rab-7L1; Rab-7-like protein 1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8934 |
| Human Swiss-Prot | O14966 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Rab 7L1 |
| Fields | |
| Gene name | RAB7L1 |
| Protein name | Ras-related protein Rab-7L1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q91YQ1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 171122 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63481 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAB7L1. AA range:115-164 |
| Specificity | Rab 7L1 Polyclonal Antibody detects endogenous levels of Rab 7L1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 28kD |
| Background | similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous., |
| Function | similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Ubiquitous., |
| Subcellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus . Golgi apparatus, trans-Golgi network . Vacuole . Cytoplasm, cytoskeleton . Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (PubMed:29212815). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847). . |
| Expression | Ubiquitous. |
Additional Images
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Western Blot analysis of various cells using Rab 7L1 Polyclonal Antibody
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Western blot analysis of lysates from HT-29 cells, using RAB7L1 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using RAB7L1 antibody.
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES3293-50
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