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Antibody Product Overview
| ELK.No | ES3330 |
| Product name | RASSF6 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | RASSF6; Ras association domain-containing protein 6 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 166824 |
| Human Swiss-Prot | Q6ZTQ3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RASSF6 |
| Fields | >>Hippo signaling pathway;>>Hippo signaling pathway - multiple species |
| Gene name | RASSF6 |
| Protein name | Ras association domain-containing protein 6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q80UQ2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RASSF6. AA range:129-178 |
| Specificity | RASSF6 Polyclonal Antibody detects endogenous levels of RASSF6 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kD |
| Background | This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012], |
| Function | function:May act as a Ras effector protein.,sequence caution:Translated as Gln.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain., |
| Subcellular location | |
| Expression | Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart. |
Additional Images
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Western Blot analysis of various cells using RASSF6 Polyclonal Antibody
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Western blot analysis of lysates from HeLa cells, using RASSF6 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from K562 cells using RASSF6 antibody.
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: AO-06-ES3330-50
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