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Antibody Product Overview
| ELK.No | ES3351 |
| Product name | Rho GDIγ rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | ARHGDIG; Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 398 |
| Human Swiss-Prot | Q99819 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Rho GDIγ |
| Fields | >>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption |
| Gene name | ARHGDIG |
| Protein name | Rho GDP-dissociation inhibitor 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q62160 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from Rho GDIγ . at AA range: 110-190 |
| Specificity | Rho GDIγ Polyclonal Antibody detects endogenous levels of Rho GDIγ protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010], |
| Function | function:Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.,similarity:Belongs to the Rho GDI family.,tissue specificity:Primarily expressed in pancreas and brain., |
| Subcellular location | Cytoplasm. |
| Expression | Primarily expressed in pancreas and brain. |
Additional Images
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Western Blot analysis of various cells using Rho GDIγ Polyclonal Antibody
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES3351-100
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