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Antibody Product Overview
| ELK.No | ES3425 |
| Product name | Septin 3 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | SEPT3; SEP3; Neuronal-specific septin-3 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 55964 |
| Human Swiss-Prot | Q9UH03 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Septin 3 |
| Fields | >>Bacterial invasion of epithelial cells;>>Shigellosis |
| Gene name | SEPT3 |
| Protein name | Neuronal-specific septin-3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 24050 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z1S5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 56003 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9WU34 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185 |
| Specificity | Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008], |
| Function | function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific., |
| Subcellular location | Cytoplasm. Cytoplasm, cytoskeleton . Cell junction, synapse . |
| Expression | Brain-specific. |
Additional Images
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Western Blot analysis of various cells using Septin 3 Polyclonal Antibody diluted at 1:1000
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Western blot analysis of various lysis using Septin 3 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysates from 293 cells, using SEPT3 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
: AO-06-ES3425-50
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