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Antibody Product Overview
| ELK.No | ES3452 |
| Product name | SLC43A1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA;IHC |
| Other name | SLC43A1; LAT3; PB39; POV1; Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8501 |
| Human Swiss-Prot | O75387 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SLC43A1 |
| Fields | |
| Gene name | SLC43A1 |
| Protein name | Large neutral amino acids transporter small subunit 3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BSM7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human LAT3. AA range:231-280 |
| Specificity | SLC43A1 Polyclonal Antibody detects endogenous levels of SLC43A1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 61kD |
| Background | SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008], |
| Function | function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells., |
| Subcellular location | Membrane ; Multi-pass membrane protein . |
| Expression | In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells. |
Additional Images
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Western Blot analysis of various cells using SLC43A1 Polyclonal Antibody
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Western blot analysis of lysates from A549 and Jurkat cells, using LAT3 Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES3452-50
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