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Antibody Product Overview
| ELK.No | ES3491 |
| Product name | SR-1F rabbit pAb |
| Reactivity | Human;Mouse;Rat;Monkey |
| Applications | WB;ELISA;IHC |
| Other name | HTR1F; HTR1EL; 5-hydroxytryptamine receptor 1F; 5-HT-1F; 5-HT1F; Serotonin receptor 1F |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3355 |
| Human Swiss-Prot | P30939 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SR-1F |
| Fields | >>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction;>>Serotonergic synapse;>>Taste transduction |
| Gene name | HTR1F |
| Protein name | 5-hydroxytryptamine receptor 1F |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 15557 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q02284 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P30940 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from human 5-HT-1F. AA range:101-150 |
| Specificity | SR-1F Polyclonal Antibody detects endogenous levels of SR-1F protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Function | function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Brain, |
Additional Images
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Western Blot analysis of various cells using SR-1F Polyclonal Antibody diluted at 1:1000
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Western blot analysis of lysates from COS7 cells, using 5-HT-1F Antibody. The lane on the right is blocked with the synthesized peptide.
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES3491-50
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