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Antibody Product Overview
| ELK.No | ES3545 |
| Product name | T2R39 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IF;ELISA |
| Other name | TAS2R39; Taste receptor type 2 member 39; T2R39; Taste receptor type 2 member 57; T2R57 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 259285 |
| Human Swiss-Prot | P59534 |
| Source | Rabbit |
| Isotype | IgG |
| Target | T2R39 |
| Fields | >>Taste transduction |
| Gene name | TAS2R39 |
| Protein name | Taste receptor type 2 member 39 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q7TQA5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAS2R39. AA range:218-267 |
| Specificity | T2R39 Polyclonal Antibody detects endogenous levels of T2R39 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 36kD |
| Background | The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015], |
| Function | function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Additional Images
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Western Blot analysis of various cells using T2R39 Polyclonal Antibody
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Immunofluorescence analysis of A549 cells, using TAS2R39 Antibody. The picture on the right is blocked with the synthesized peptide.
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Western blot analysis of lysates from HepG2 cells, using TAS2R39 Antibody. The lane on the right is blocked with the synthesized peptide.
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Western blot analysis of the lysates from HepG2 cells using TAS2R39 antibody.
: AO-06-ES3545-100
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