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Antibody Product Overview
| ELK.No | ES3830 |
| Product name | RASSF8 rabbit pAb |
| Reactivity | Human;Rat |
| Applications | WB;ELISA |
| Other name | RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 11228 |
| Human Swiss-Prot | Q8NHQ8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RASSF8 |
| Fields | |
| Gene name | RASSF8 |
| Protein name | Ras association domain-containing protein 8 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8CJ96 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from RASSF8 . at AA range: 60-140 |
| Specificity | RASSF8 Polyclonal Antibody detects endogenous levels of RASSF8 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 48kD |
| Background | This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011], |
| Function | disease:A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly, also referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses [MIM:608180]. Reciprocal translocation t(12;22)(p11.2;q13.3) with FBLN1.,similarity:Contains 1 Ras-associating domain.,tissue specificity:Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis., |
| Subcellular location | |
| Expression | Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis. |
Additional Images
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Western Blot analysis of extracts from rat stomach, using RASSF8 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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: AO-06-ES3830-50
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