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Antibody Product Overview
| ELK.No | ES3831 |
| Product name | SCML2 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB; ELISA;IHC |
| Other name | SCML2; Sex comb on midleg-like protein 2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10389 |
| Human Swiss-Prot | Q9UQR0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SCML2 |
| Fields | |
| Gene name | SCML2 |
| Protein name | Sex comb on midleg-like protein 2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from the Internal region of human SCML2. |
| Specificity | SCML2 Polyclonal Antibody detects endogenous levels of SCML2 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 77kD |
| Background | This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010], |
| Function | function:Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SCM family.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 MBT repeats.,tissue specificity:Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary., |
| Subcellular location | Nucleus . |
| Expression | Highly expressed in placenta, thymus and testis. Detected at lower levels in brain, liver, skeletal muscle, pancreas and ovary. |
Additional Images
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Western Blot analysis of extracts from 293 cells, using SCML2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES3831-50
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