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Antibody Product Overview
| ELK.No | ES3946 |
| Product name | Kallistatin rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | SERPINA4; KST; PI4; Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5267 |
| Human Swiss-Prot | P29622 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Kallistatin |
| Fields | |
| Gene name | SERPINA4 |
| Protein name | Kallistatin |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human SERPINA4. AA range:161-210 |
| Specificity | Kallistatin Polyclonal Antibody detects endogenous levels of Kallistatin protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 47kD |
| Background | function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Function | function:Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.,miscellaneous:Heparin blocks kallistatin's complex formation with tissue kallikrein and abolishes its inhibitory effect on tissue kallikrein's activity.,PTM:The N-terminus is blocked.,similarity:Belongs to the serpin family.,subunit:Monomer and some homodimers.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Subcellular location | Secreted. |
| Expression | Expressed by the liver and secreted in plasma. |
Additional Images
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Western Blot analysis of K562 cells using Kallistatin Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
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Western blot analysis of lysate from K562 cells, using SERPINA4 Antibody.
: AO-06-ES3946-50
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