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Antibody Product Overview
| ELK.No | ES3997 |
| Product name | CD248 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | CD248; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 57124 |
| Human Swiss-Prot | Q9HCU0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CD248 |
| Fields | |
| Gene name | CD248 |
| Protein name | Endosialin |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q91V98 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CD248. AA range:341-390 |
| Specificity | CD248 Polyclonal Antibody detects endogenous levels of CD248 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 80kD |
| Background | function:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts., |
| Function | function:May play a role in tumor angiogenesis.,online information:Endosialin,PTM:May be N-glycosylated.,PTM:O-glycosylated with sialylated oligosaccharides.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts., |
| Subcellular location | Membrane ; Single-pass type I membrane protein . |
| Expression | Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts. |
Additional Images
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Western Blot analysis of HepG2 cells using CD248 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysate from HepG2 cells, using CD248 Antibody.
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: AO-06-ES3997-100
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