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Antibody Product Overview
| ELK.No | ES4035 |
| Product name | IL-28 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;IHC;IF;ELISA |
| Other name | IL28A; IFNL2; ZCYTO20; Interleukin-28A; IL-28A; Cytokine Zcyto20; Interferon lambda-2; IFN-lambda-2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 282616 |
| Human Swiss-Prot | Q8IZJ0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | IL-28 |
| Fields | >>Cytokine-cytokine receptor interaction;>>JAK-STAT signaling pathway |
| Gene name | IL28A |
| Protein name | Interleukin-28A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 330496 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q4VK74 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL28A. AA range:131-180 |
| Specificity | IL-28 Polyclonal Antibody detects endogenous levels of IL-28 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 25kD |
| Background | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008], |
| Function | caution:It is uncertain whether Met-1 or Met-5 is the initiator.,function:Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.,induction:By viral infections or double stranded RNA.,online information:Interleukin-28 entry,similarity:Belongs to the IL-28/IL-29 family., |
| Subcellular location | Secreted . |
| Expression | Pooled, |
Additional Images
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Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
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Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
: AO-06-ES4035-50
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