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Antibody Product Overview
| ELK.No | ES4099 |
| Product name | SCYL1BP1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | GORAB; NTKLBP1; SCYL1BP1; RAB6-interacting golgin; N-terminal kinase-like-binding protein 1; NTKL-BP1; NTKL-binding protein 1; hNTKL-BP1; SCY1-like 1-binding protein 1; SCYL1-BP1; SCYL1-binding protein 1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 92344 |
| Human Swiss-Prot | Q5T7V8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SCYL1BP1 |
| Fields | >>p53 signaling pathway |
| Gene name | GORAB |
| Protein name | RAB6-interacting golgin |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 98376 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BRM2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 304923 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | B1H222 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB. AA range:1-50 |
| Specificity | SCYL1BP1 Polyclonal Antibody detects endogenous levels of SCYL1BP1 protein. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kD |
| Background | golgin, RAB6 interacting(GORAB) Homo sapiens This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009], |
| Function | caution:It is uncertain whether Met-1 or Met-26 is the initiator.,disease:Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.,similarity:Belongs to the GORAB family.,subunit:Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6., |
| Subcellular location | Cytoplasm . Golgi apparatus . |
| Expression | Embryo,Pancreas,Testis,Trachea, |
Additional Images
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Western Blot analysis of AD293 cells using SCYL1BP1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western blot analysis of lysate from AD293 cells, using GORAB Antibody.
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Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES4099-100
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